Quantitative PPARγ expression affects the balance between tolerance and immunity

PPARγ modulates energy metabolism and inflammation. However, its specific functions in the balance of immunity in vivo have been explored incompletely. In this study, by the age of 14 mo, Pparg(C/−) mice with PPARγ expression at 25% of the normal level exhibited high autoantibody levels and develope...

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Vydáno v:Sci Rep
Hlavní autoři: Liu, Ya-Hui, Tsai, Yau-Sheng, Lin, Shih-Chieh, Liao, Nan-Shih, Jan, Ming-Shiou, Liang, Chung-Tiang, Hsu, Shih-Wen, Chen, Wen-Chung, Sung, Junne-Ming, Maeda, Nobuyo, Tsai, Pei-Jane
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879582/
https://ncbi.nlm.nih.gov/pubmed/27221351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26646
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