Quantitative PPARγ expression affects the balance between tolerance and immunity

PPARγ modulates energy metabolism and inflammation. However, its specific functions in the balance of immunity in vivo have been explored incompletely. In this study, by the age of 14 mo, Pparg(C/−) mice with PPARγ expression at 25% of the normal level exhibited high autoantibody levels and develope...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Ya-Hui, Tsai, Yau-Sheng, Lin, Shih-Chieh, Liao, Nan-Shih, Jan, Ming-Shiou, Liang, Chung-Tiang, Hsu, Shih-Wen, Chen, Wen-Chung, Sung, Junne-Ming, Maeda, Nobuyo, Tsai, Pei-Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879582/
https://ncbi.nlm.nih.gov/pubmed/27221351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26646
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