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PPARγ Level Contributes to Structural Integrity and Component Production of Elastic Fibers in the Aorta

Loss of integrity and massive disruption of elastic fibers are key features of abdominal aortic aneurysm (AAA). Peroxisome proliferator-activated receptor γ (PPARγ) has been shown to attenuate AAA through inhibition of inflammation and proteolytic degradation. However, its involvement in elastogenes...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Tai, Haw-Chih, Tsai, Pei-Jane, Chen, Ju-Yi, Lai, Chao-Han, Wang, Kuan-Chieh, Teng, Shih-Hua, Lin, Shih-Chieh, Chang, Alice Y. W., Jiang, Meei-Jyh, Li, Yi-Heng, Wu, Hua-Lin, Maeda, Nobuyo, Tsai, Yau-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865434/
https://ncbi.nlm.nih.gov/pubmed/27045031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07367
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