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Inhibitory effect of PPARγ on NLRP3 inflammasome activation

Rationale: Stimulation of the NLRP3 inflammasome by metabolic byproducts is known to result in inflammatory responses and metabolic diseases. However, how the host controls aberrant NLRP3 inflammasome activation remains unclear. PPARγ, a known regulator of energy metabolism, plays an anti-inflammato...

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Bibliografiske detaljer
Udgivet i:Theranostics
Main Authors: Yang, Ching-Chun, Wu, Chih-Hsing, Lin, Ta-Chun, Cheng, Yi-Ning, Chang, Chin-Sung, Lee, Kuo-Ting, Tsai, Pei-Jane, Tsai, Yau-Sheng
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797672/
https://ncbi.nlm.nih.gov/pubmed/33500734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.46873
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