PPARγ activation improves the microenvironment of perivascular adipose tissue and attenuates aortic stiffening in obesity

BACKGROUND: Obesity-related cardiovascular risk, end points, and mortality are strongly related to arterial stiffening. Current therapeutic approaches for arterial stiffening are not focused on direct targeting within the vessel. Perivascular adipose tissue (PVAT) surrounding the artery has been sho...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Chen, Ju-Yi, Wu, Yi-Pin, Li, Chih-Yi, Jheng, Huei-Fen, Kao, Ling-Zhen, Yang, Ching-Chun, Leu, Sy-Ying, Lien, I-Chia, Weng, Wen-Tsan, Tai, Haw-Chih, Chiou, Yu-Wei, Tang, Ming-Jer, Tsai, Pei-Jane, Tsai, Yau-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008548/
https://ncbi.nlm.nih.gov/pubmed/33781257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-021-00720-y
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