Dominant-negative loss of PPARγ function enhances smooth muscle cell proliferation, migration, and vascular remodeling

OBJECTIVE: The Peroxisome Proliferator Activated Receptor-gamma (PPARγ) protein is a nuclear transcriptional activator with importance in diabetes management as the molecular target for the thiazolidinedione (TZD) family of drugs. Substantial evidence indicates that the TZD family of PPARγ agonists...

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Main Authors: Meredith, Dane, Panchatcharam, Manikandan, Miriyala, Sumitra, Tsai, Yau-Sheng, Morris, Andrew J., Maeda, Nobuyo, Stouffer, George A., Smyth, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773202/
https://ncbi.nlm.nih.gov/pubmed/19179641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.184234
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