Prospective Design of Anti‐Transferrin Receptor Bispecific Antibodies for Optimal Delivery into the Human Brain

Anti‐transferrin receptor (TfR)‐based bispecific antibodies have shown promise for boosting antibody uptake in the brain. Nevertheless, there are limited data on the molecular properties, including affinity required for successful development of TfR‐based therapeutics. A complex nonmonotonic relatio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:CPT Pharmacometrics Syst Pharmacol
Egile Nagusiak: Kanodia, JS, Gadkar, K, Bumbaca, D, Zhang, Y, Tong, RK, Luk, W, Hoyte, K, Lu, Y, Wildsmith, KR, Couch, JA, Watts, RJ, Dennis, MS, Ernst, JA, Scearce‐Levie, K, Atwal, JK, Ramanujan, S, Joseph, S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879477/
https://ncbi.nlm.nih.gov/pubmed/27299941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12081
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak