gPKPDSim: a SimBiology(®)-based GUI application for PKPD modeling in drug development

Modeling and simulation (M&S) is increasingly used in drug development to characterize pharmacokinetic-pharmacodynamic (PKPD) relationships and support various efforts such as target feasibility assessment, molecule selection, human PK projection, and preclinical and clinical dose and schedule d...

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Bibliografiske detaljer
Udgivet i:J Pharmacokinet Pharmacodyn
Main Authors: Hosseini, Iraj, Gajjala, Anita, Bumbaca Yadav, Daniela, Sukumaran, Siddharth, Ramanujan, Saroja, Paxson, Ricardo, Gadkar, Kapil
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2018
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845055/
https://ncbi.nlm.nih.gov/pubmed/29302838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-017-9562-9
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