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TCR signaling by conventional CD4(+) T cells is required for optimal maintenance of peripheral regulatory T cell numbers
To maintain immune tolerance, regulatory T cell (Treg) numbers must be closely indexed to the number of conventional T cells (Tconvs) so that an adequate Treg:Tconv ratio can be maintained. Two factors important in this process are the cytokine interleukin‐2 (IL‐2) and T cell receptor (TCR) stimulat...
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| Publicado no: | Immun Inflamm Dis |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879461/ https://ncbi.nlm.nih.gov/pubmed/27891224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.100 |
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