Nalaganje...
Cell-autonomous role of TGFβ and IL-2 receptors in CD4(+) and CD8(+) inducible regulatory T-cell generation during GVHD
FoxP3(+) regulatory T cells (Tregs) suppress GVHD while preserving graft-versus-tumor effects, making them an attractive target for GVHD therapy. The donor-derived Treg pool can potentially be derived from the expansion of preexisting natural Tregs (nTregs) or from de novo generation of inducible Tr...
Shranjeno v:
| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369690/ https://ncbi.nlm.nih.gov/pubmed/22496155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-367987 |
| Oznake: |
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