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Cutting Edge: IL-2 Signals Determine the Degree of TCR Signaling Necessary to Support Regulatory T Cell Proliferation In Vivo
To ensure immune tolerance, regulatory T cell (Treg) numbers must be maintained by cell division. This process has been thought to be strictly dependent on the Treg TCR interacting with MHC class II (MHCII). Here, we report that Treg division does not absolutely require cell-autonomous TCR signaling...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3381992/ https://ncbi.nlm.nih.gov/pubmed/22623329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200507 |
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