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Cutting Edge: IL-2 Signals Determine the Degree of TCR Signaling Necessary to Support Regulatory T Cell Proliferation In Vivo

To ensure immune tolerance, regulatory T cell (Treg) numbers must be maintained by cell division. This process has been thought to be strictly dependent on the Treg TCR interacting with MHC class II (MHCII). Here, we report that Treg division does not absolutely require cell-autonomous TCR signaling...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zou, Tao, Satake, Atsushi, Corbo, Evann, Schmidt, Amanda M., Farrar, Michael A., Maltzman, Jonathan S., Kambayashi, Taku
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381992/
https://ncbi.nlm.nih.gov/pubmed/22623329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200507
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