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Regulatory T cells constrain the TCR repertoire of antigen‐stimulated conventional CD4 T cells
To analyze the potential role of Tregs in controlling the TCR repertoire breadth to a non‐self‐antigen, a TCRβ transgenic mouse model (EF4.1) expressing a limited, yet polyclonal naïve T‐cell repertoire was used. The response of EF4.1 mice to an I‐Ab‐associated epitope of the F‐MuLV envelope protein...
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| 出版年: | EMBO J |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5793804/ https://ncbi.nlm.nih.gov/pubmed/29263148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796881 |
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