TCR repertoires of thymic conventional and regulatory T cells: Identification and characterization of both unique and shared TCR sequences

Thymic regulatory T cells (tTreg) are critical in maintenance of normal T cell immunity and tolerance. The role of TCR in tTreg cell selection remains incompletely understood. Here we assessed TCRα and TCRβ sequences of mouse tTreg and conventional thymic CD4(+) T (Tconv) cells by high throughput se...

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Udgivet i:J Immunol
Main Authors: Ko, Annette, Watanabe, Masashi, Nguyen, Thomas, Shi, Alvin, Achour, Achouak, Zhang, Baojun, Sun, Xiaoping, Wang, Qun, Zhuang, Yuan, Weng, Nan-ping, Hodes, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002224/
https://ncbi.nlm.nih.gov/pubmed/31924652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901006
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