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MHC drives TCR repertoire shaping, but not maturation, in recent thymic emigrants

After developing in the thymus, recent thymic emigrants (RTEs) enter the lymphoid periphery and undergo a maturation process as they transition into the mature naïve (MN) T cell compartment. This maturation presumably shapes RTEs into a pool of T cells best fit to function robustly in the periphery...

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Detalhes bibliográficos
Main Authors: Houston, Evan G., Fink, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782759/
https://ncbi.nlm.nih.gov/pubmed/19915060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902313
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