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Recent thymic emigrants are tolerized in the absence of inflammation
T cell development requires a period of postthymic maturation. Why this is the case has remained a mystery, particularly given the rigors of intrathymic developmental checkpoints, successfully traversed by only ∼5% of thymocytes. We now show that the first few weeks of T cell residence in the lympho...
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Publicado no: | J Exp Med |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886366/ https://ncbi.nlm.nih.gov/pubmed/27139493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151990 |
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