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Recent thymic emigrants are tolerized in the absence of inflammation
T cell development requires a period of postthymic maturation. Why this is the case has remained a mystery, particularly given the rigors of intrathymic developmental checkpoints, successfully traversed by only ∼5% of thymocytes. We now show that the first few weeks of T cell residence in the lympho...
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| Publicado en: | J Exp Med |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886366/ https://ncbi.nlm.nih.gov/pubmed/27139493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151990 |
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