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Highly Dynamic and Specific Phosphatidylinositol 4,5-Bisphosphate, Septin, and Cell Wall Integrity Pathway Responses Correlate with Caspofungin Activity against Candida albicans
Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)] activates the yeast cell wall integrity pathway. Candida albicans exposure to caspofungin results in the rapid redistribution of PI(4,5)P(2) and septins to plasma membrane foci and subsequent fungicidal effects. We studied C. albicans PI(4,5)P(2) a...
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| Published in: | Antimicrob Agents Chemother |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879351/ https://ncbi.nlm.nih.gov/pubmed/27021331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02711-15 |
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