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Highly Dynamic and Specific Phosphatidylinositol 4,5-Bisphosphate, Septin, and Cell Wall Integrity Pathway Responses Correlate with Caspofungin Activity against Candida albicans

Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)] activates the yeast cell wall integrity pathway. Candida albicans exposure to caspofungin results in the rapid redistribution of PI(4,5)P(2) and septins to plasma membrane foci and subsequent fungicidal effects. We studied C. albicans PI(4,5)P(2) a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Antimicrob Agents Chemother
मुख्य लेखकों: Badrane, Hassan, Nguyen, M. Hong, Clancy, Cornelius J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879351/
https://ncbi.nlm.nih.gov/pubmed/27021331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02711-15
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