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Caspofungin Kills Candida albicans by Causing both Cellular Apoptosis and Necrosis

Caspofungin exerts candidacidal activity by inhibiting cell wall (1,3)-β-d-glucan synthesis. We investigated the physiologic mechanisms of caspofungin-induced Candida albicans cell death. Apoptosis (programmed cell death) and necrosis were studied after C. albicans SC5314 cells were exposed to caspo...

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Detalhes bibliográficos
Main Authors: Hao, Binghua, Cheng, Shaoji, Clancy, Cornelius J., Nguyen, M. Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535936/
https://ncbi.nlm.nih.gov/pubmed/23114781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01366-12
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