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Caspofungin Kills Candida albicans by Causing both Cellular Apoptosis and Necrosis
Caspofungin exerts candidacidal activity by inhibiting cell wall (1,3)-β-d-glucan synthesis. We investigated the physiologic mechanisms of caspofungin-induced Candida albicans cell death. Apoptosis (programmed cell death) and necrosis were studied after C. albicans SC5314 cells were exposed to caspo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535936/ https://ncbi.nlm.nih.gov/pubmed/23114781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01366-12 |
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