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Efg1 and Cas5 Orchestrate Cell Wall Damage Response to Caspofungin in Candida albicans

Echinocandins are recommended as the first-line drugs for the treatment of systemic candidiasis. Cas5 is a key transcription factor involved in the response to cell wall damage induced by echinocandins. In this study, through a genetic screen, we identified a second transcription factor, Efg1, that...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Xiong, Kang, Su, Chang, Sun, Qiangqiang, Lu, Yang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848995/
https://ncbi.nlm.nih.gov/pubmed/33168610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01584-20
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