A Subset of Patients with Acute Myeloid Leukemia Has Leukemia Cells Characterized by Chemokine Responsiveness and Altered Expression of Transcriptional as well as Angiogenic Regulators

Acute myeloid leukemia (AML) is an aggressive and heterogeneous bone marrow malignancy, the only curative treatment being intensive chemotherapy eventually in combination with allogeneic stem cell transplantation. Both the AML and their neighboring stromal cells show constitutive chemokine release,...

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Publicat a:Front Immunol
Autors principals: Brenner, Annette K., Reikvam, Håkon, Bruserud, Øystein
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879142/
https://ncbi.nlm.nih.gov/pubmed/27252705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00205
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