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A Subset of Patients with Acute Myeloid Leukemia Has Leukemia Cells Characterized by Chemokine Responsiveness and Altered Expression of Transcriptional as well as Angiogenic Regulators

Acute myeloid leukemia (AML) is an aggressive and heterogeneous bone marrow malignancy, the only curative treatment being intensive chemotherapy eventually in combination with allogeneic stem cell transplantation. Both the AML and their neighboring stromal cells show constitutive chemokine release,...

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Publié dans:Front Immunol
Auteurs principaux: Brenner, Annette K., Reikvam, Håkon, Bruserud, Øystein
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879142/
https://ncbi.nlm.nih.gov/pubmed/27252705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00205
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