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Therapeutic Targeting the Cell Division Cycle 25 (CDC25) Phosphatases in Human Acute Myeloid Leukemia — The Possibility to Target Several Kinases through Inhibition of the Various CDC25 Isoforms

The cell division cycle 25 (CDC25) phosphatases include CDC25A, CDC25B and CDC25C. These three molecules are important regulators of several steps in the cell cycle, including the activation of various cyclin-dependent kinases (CDKs). CDC25s seem to have a role in the development of several human ma...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Brenner, Annette K., Reikvam, Håkon, Lavecchia, Antonio, Bruserud, Øystein
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270710/
https://ncbi.nlm.nih.gov/pubmed/25397735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191118414
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