Therapeutic Targeting the Cell Division Cycle 25 (CDC25) Phosphatases in Human Acute Myeloid Leukemia — The Possibility to Target Several Kinases through Inhibition of the Various CDC25 Isoforms

The cell division cycle 25 (CDC25) phosphatases include CDC25A, CDC25B and CDC25C. These three molecules are important regulators of several steps in the cell cycle, including the activation of various cyclin-dependent kinases (CDKs). CDC25s seem to have a role in the development of several human ma...

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發表在:Molecules
Main Authors: Brenner, Annette K., Reikvam, Håkon, Lavecchia, Antonio, Bruserud, Øystein
格式: Artigo
語言:Inglês
出版: MDPI 2014
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270710/
https://ncbi.nlm.nih.gov/pubmed/25397735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191118414
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