A Subset of Patients with Acute Myeloid Leukemia Has Leukemia Cells Characterized by Chemokine Responsiveness and Altered Expression of Transcriptional as well as Angiogenic Regulators

Acute myeloid leukemia (AML) is an aggressive and heterogeneous bone marrow malignancy, the only curative treatment being intensive chemotherapy eventually in combination with allogeneic stem cell transplantation. Both the AML and their neighboring stromal cells show constitutive chemokine release,...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Brenner, Annette K., Reikvam, Håkon, Bruserud, Øystein
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879142/
https://ncbi.nlm.nih.gov/pubmed/27252705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00205
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