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T-cell responsiveness to an oncogenic peripheral protein and spontaneous autoimmunity in transgenic mice.

Why T cells develop autoimmune reactivity to some antigens and tolerance to others is unknown. Various mechanisms can provide for T-cell tolerance. These include deletion in the thymus, exhaustive differentiation in the periphery, T-cell receptor and coreceptor downregulation, and anergy. Which mech...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:Proc Natl Acad Sci U S A
Үндсэн зохиолчид: Geiger, T, Gooding, L R, Flavell, R A
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: National Academy of Sciences 1992
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48788/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1532662/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2985
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