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TPC2 controls pigmentation by regulating melanosome pH and size
Melanin is responsible for pigmentation of skin and hair and is synthesized in a specialized organelle, the melanosome, in melanocytes. A genome-wide association study revealed that the two pore segment channel 2 (TPCN2) gene is strongly linked to pigmentation variations. TPCN2 encodes the two-pore...
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| Foilsithe in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4878521/ https://ncbi.nlm.nih.gov/pubmed/27140606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600108113 |
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