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Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH
The production of melanin increases skin pigmentation and reduces the risk of skin cancer. Melanin production depends on the pH of melanosomes, which are more acidic in lighter-skinned than in darker-skinned people. We showed that inhibition of soluble adenylyl cyclase (sAC) controlled pigmentation...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6540755/ https://ncbi.nlm.nih.gov/pubmed/30401788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aau7987 |
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