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TPC2 mediates new mechanisms of platelet dense granule membrane dynamics through regulation of Ca(2+) release
Platelet dense granules (PDGs) are acidic calcium stores essential for normal hemostasis. They develop from late endosomal compartments upon receiving PDG-specific proteins through vesicular trafficking, but their maturation process is not well understood. Here we show that two-pore channel 2 (TPC2)...
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| Publicado no: | Mol Biol Cell |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4569316/ https://ncbi.nlm.nih.gov/pubmed/26202466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-01-0058 |
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