Cargando...

TPC2 mediates new mechanisms of platelet dense granule membrane dynamics through regulation of Ca(2+) release

Platelet dense granules (PDGs) are acidic calcium stores essential for normal hemostasis. They develop from late endosomal compartments upon receiving PDG-specific proteins through vesicular trafficking, but their maturation process is not well understood. Here we show that two-pore channel 2 (TPC2)...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Biol Cell
Autores principales: Ambrosio, Andrea L., Boyle, Judith A., Di Pietro, Santiago M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569316/
https://ncbi.nlm.nih.gov/pubmed/26202466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-01-0058
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!