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Imatinib for Melanomas Harboring Mutationally Activated or Amplified KIT Arising on Mucosal, Acral, and Chronically Sun-Damaged Skin

PURPOSE: Amplifications and mutations in the KIT proto-oncogene in subsets of melanomas provide therapeutic opportunities. PATIENTS AND METHODS: We conducted a multicenter phase II trial of imatinib in metastatic mucosal, acral, or chronically sun-damaged (CSD) melanoma with KIT amplifications and/o...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Clin Oncol
मुख्य लेखकों: Hodi, F. Stephen, Corless, Christopher L., Giobbie-Hurder, Anita, Fletcher, Jonathan A., Zhu, Meijun, Marino-Enriquez, Adrian, Friedlander, Philip, Gonzalez, Rene, Weber, Jeffrey S., Gajewski, Thomas F., O'Day, Steven J., Kim, Kevin B., Lawrence, Donald, Flaherty, Keith T., Luke, Jason J., Collichio, Frances A., Ernstoff, Marc S., Heinrich, Michael C., Beadling, Carol, Zukotynski, Katherine A., Yap, Jeffrey T., Van den Abbeele, Annick D., Demetri, George D., Fisher, David E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Clinical Oncology 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878082/
https://ncbi.nlm.nih.gov/pubmed/23775962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.47.7836
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