Metabolic response by FDG-PET to imatinib correlates with exon 11 KIT mutation and predicts outcome in patients with mucosal melanoma

BACKGROUND: In patients with metastatic melanoma and KIT amplifications and/or mutations, therapy with imatinib mesylate may prolong survival. (18)F-labeled 2-fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/CT may be used to assess metabolic response. We investigated associations of metabolic response, mut...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Imaging
Auteurs principaux: Zukotynski, Katherine, Yap, Jeffrey T, Giobbie-Hurder, Anita, Weber, Jeffrey, Gonzalez, Rene, Gajewski, Thomas F, O’Day, Steven, Kim, Kevin, Hodi, F Stephen, Van den Abbeele, Annick D
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331835/
https://ncbi.nlm.nih.gov/pubmed/25609545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40644-014-0030-0
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