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A sensitive NanoString-based assay to score STK11 (LKB1) pathway disruption in lung adenocarcinoma
INTRODUCTION: Serine/threonine kinase 11 (STK11), better known as LKB1, is a tumor-suppressor commonly mutated in lung adenocarcinoma (LUAD). Previous work has shown that mutational inactivation of the STK11 pathway may serve as a predictive biomarker for cancer treatments including phenformin and C...
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| 出版年: | J Thorac Oncol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4877210/ https://ncbi.nlm.nih.gov/pubmed/26917230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2016.02.009 |
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