A sensitive NanoString-based assay to score STK11 (LKB1) pathway disruption in lung adenocarcinoma

INTRODUCTION: Serine/threonine kinase 11 (STK11), better known as LKB1, is a tumor-suppressor commonly mutated in lung adenocarcinoma (LUAD). Previous work has shown that mutational inactivation of the STK11 pathway may serve as a predictive biomarker for cancer treatments including phenformin and C...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Chen, Lu, Engel, Brienne E., Welsh, Eric A., Yoder, Sean J., Brantley, Stephen G., Chen, Dung-Tsa, Beg, Amer A., Cao, Chunxia, Kaye, Frederic J., Haura, Eric B., Schabath, Matthew B., Cress, W. Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877210/
https://ncbi.nlm.nih.gov/pubmed/26917230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2016.02.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados