Differential association of STK11 and TP53 with KRAS mutation-associated gene expression, proliferation and immune surveillance in lung adenocarcinoma

While mutations in the KRAS oncogene are amongst the most prevalent in human cancer, there are few successful treatments to target these tumors. It is also likely that heterogeneity in KRAS-mutant tumor biology significantly contributes to the response to therapy. We hypothesized that presence of co...

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Publicat a:Oncogene
Autors principals: Schabath, Matthew B., Welsh, Eric A., Fulp, William J., Chen, Lu, Teer, Jamie K., Thompson, Zachary J., Engel, Brienne E., Xie, Mengyu, Berglund, Anders E., Creelan, Ben C., Antonia, Scott J., Gray, Jhanelle E., Eschrich, Steven, Chen, Dung-Tsa, Cress, W. Douglas, Haura, Eric B., Beg, Amer A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837098/
https://ncbi.nlm.nih.gov/pubmed/26477306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.375
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