Application of Bayesian predictive probability for interim futility analysis in single-arm phase II trial

BACKGROUND: Bayesian predictive probability design, with a binary endpoint, is gaining attention for the phase II trial due to its innovative strategy. To make the Bayesian design more accessible, we elucidate this Bayesian approach with a R package to streamline a statistical plan, so biostatistici...

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Udgivet i:Transl Cancer Res
Main Authors: Chen, Dung-Tsa, Schell, Michael J., Fulp, William J., Pettersson, Fredrik, Kim, Sungjune, Gray, Jhanelle E., Haura, Eric B.
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2019
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711387/
https://ncbi.nlm.nih.gov/pubmed/31456910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tcr.2019.05.17
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