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The utility of Bayesian predictive probabilities for interim monitoring of clinical trials

BACKGROUND: Bayesian predictive probabilities can be used for interim monitoring of clinical trials to estimate the probability of observing a statistically significant treatment effect if the trial were to continue to its predefined maximum sample size. PURPOSE: We explore settings in which Bayesia...

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Pubblicato in:Clin Trials
Autori principali: Saville, Benjamin R., Connor, Jason T., Ayers, Gregory D, Alvarez, JoAnn
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247348/
https://ncbi.nlm.nih.gov/pubmed/24872363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774514531352
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