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Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions

Tumor-associated macrophages (TAMs) are critically important in the context of solid tumor progression. Counterintuitively, these host immune cells can often support tumor cells along the path from primary tumor to metastatic colonization and growth. Thus, the ability to transform protumor TAMs into...

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書目詳細資料
發表在:Int J Nanomedicine
Main Authors: Ortega, Ryan A, Barham, Whitney, Sharman, Kavya, Tikhomirov, Oleg, Giorgio, Todd D, Yull, Fiona E
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876941/
https://ncbi.nlm.nih.gov/pubmed/27274241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S93483
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