Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions

Tumor-associated macrophages (TAMs) are critically important in the context of solid tumor progression. Counterintuitively, these host immune cells can often support tumor cells along the path from primary tumor to metastatic colonization and growth. Thus, the ability to transform protumor TAMs into...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Ortega, Ryan A, Barham, Whitney, Sharman, Kavya, Tikhomirov, Oleg, Giorgio, Todd D, Yull, Fiona E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876941/
https://ncbi.nlm.nih.gov/pubmed/27274241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S93483
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge