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Heterologous vaccination and checkpoint blockade synergize to induce anti-leukemia immunity

Checkpoint blockade-based immunotherapies are effective in cancers with high numbers of non-synonymous mutations. In contrast, current paradigms suggest that such approaches will be ineffective in cancers with few non-synonymous mutations. To examine this issue we made use of a murine model of BCR-A...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Manlove, Luke S., Schenkel, Jason M., Manlove, Kezia R., Pauken, Kristen E., Williams, Richard T., Vezys, Vaiva, Farrar, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875863/
https://ncbi.nlm.nih.gov/pubmed/27183622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600130
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