PLGA-particle vaccine carrying TLR3/RIG-I ligand Riboxxim synergizes with immune checkpoint blockade for effective anti-cancer immunotherapy

With emerging supremacy, cancer immunotherapy has evolved as a promising therapeutic modality compared to conventional antitumor therapies. Cancer immunotherapy composed of biodegradable poly(lactic-co-glycolic acid) (PLGA) particles containing antigens and toll-like receptor ligands induces vigorou...

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Vydáno v:Nat Commun
Hlavní autoři: Koerner, Julia, Horvath, Dennis, Herrmann, Valerie L., MacKerracher, Anna, Gander, Bruno, Yagita, Hideo, Rohayem, Jacques, Groettrup, Marcus
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131648/
https://ncbi.nlm.nih.gov/pubmed/34006895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23244-3
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