Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity

Systemic treatment with the active transcription inhibitor lurbinectedin aims at inducing tumor cell death in hyperproliferative neoplasms. Here we show that cell death induced by lurbinectedin reinstates and enhances systemic anticancer immune responses. Lurbinectedin treatment showed traits of imm...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncoimmunology
Egile Nagusiak: Xie, Wei, Forveille, Sabrina, Iribarren, Kristina, Sauvat, Allan, Senovilla, Laura, Wang, Yan, Humeau, Juliette, Perez-Lanzon, Maria, Zhou, Heng, Martínez-Leal, Juan F., Kroemer, Guido, Kepp, Oliver
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2019
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791417/
https://ncbi.nlm.nih.gov/pubmed/31646106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1656502
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