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Datopotamab deruxtecan induces hallmarks of immunogenic cell death

Antibody-drug conjugates (ADCs) offer a strategy for targeted delivery of cytotoxic agents to cancer cells. In this study, we investigated the mechanism of action of datopotamab deruxtecan, an ADC composed of a monoclonal antibody targeting tumor-associated calcium signal transducer 2 (TACSTD2, also...

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Principais autores: Sabrina Forveille, Marion Leduc, Allan Sauvat, Guido Kroemer, Oliver Kepp
Formato: Artigo
Idioma:Inglês
Publicado: Shared Science Publishers OG 2025-08-01
Series:Cell Stress
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Acceso en liña:http://microbialcell.com/researcharticles/2025a-forveille-cell-stress
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