Datopotamab deruxtecan induces hallmarks of immunogenic cell death

Antibody-drug conjugates (ADCs) offer a strategy for targeted delivery of cytotoxic agents to cancer cells. In this study, we investigated the mechanism of action of datopotamab deruxtecan, an ADC composed of a monoclonal antibody targeting tumor-associated calcium signal transducer 2 (TACSTD2, also...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sabrina Forveille, Marion Leduc, Allan Sauvat, Guido Kroemer, Oliver Kepp
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Shared Science Publishers OG 2025-08-01
Saila:Cell Stress
Gaiak:
anticancer immunotherapy
antibody drug conjugate
bystander effect
Sarrera elektronikoa:http://microbialcell.com/researcharticles/2025a-forveille-cell-stress
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