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Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity

Systemic treatment with the active transcription inhibitor lurbinectedin aims at inducing tumor cell death in hyperproliferative neoplasms. Here we show that cell death induced by lurbinectedin reinstates and enhances systemic anticancer immune responses. Lurbinectedin treatment showed traits of imm...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Xie, Wei, Forveille, Sabrina, Iribarren, Kristina, Sauvat, Allan, Senovilla, Laura, Wang, Yan, Humeau, Juliette, Perez-Lanzon, Maria, Zhou, Heng, Martínez-Leal, Juan F., Kroemer, Guido, Kepp, Oliver
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791417/
https://ncbi.nlm.nih.gov/pubmed/31646106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1656502
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