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Adaptive immunity to leukemia is inhibited by cross-reactive induced regulatory T cells

BCR-ABL(+) acute lymphoblastic leukemia patients have transient responses to current therapies. However, the fusion of BCR to ABL generates a potential leukemia-specific antigen that could be a target for immunotherapy. We demonstrate that the immune system can limit BCR-ABL(+) leukemia progression...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Manlove, Luke S., Berquam-Vrieze, Katherine E., Pauken, Kristen E., Williams, Richard T., Jenkins, Marc K., Farrar, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592825/
https://ncbi.nlm.nih.gov/pubmed/26378075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501291
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