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Crystal structure and functional implication of the RUN domain of human NESCA
NESCA, a newly discovered signaling adapter protein in the NGF-pathway, contains a RUN domain at its N-terminus. Here we report the crystal structure of the NESCA RUN domain determined at 2.0-Å resolution. The overall fold of the NESCA RUN domain comprises nine helices, resembling the RUN domain of...
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| Publicado en: | Protein Cell |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Higher Education Press
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875354/ https://ncbi.nlm.nih.gov/pubmed/22821014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-012-2052-3 |
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