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Crystal structure of human NLRP12 PYD domain and implication in homotypic interaction
NLRP12 is a NOD-like receptor that plays multiple roles in both inflammation and tumorigenesis. Despite the importance, little is known about its mechanism of action at the molecular level. Here, we report the crystal structure of NLRP12 PYD domain at 1.70 Å fused with an maltose-binding protein (MB...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5749810/ https://ncbi.nlm.nih.gov/pubmed/29293680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190547 |
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