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Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein
The caspase-recruitment domain (CARD) mediates homotypic protein–protein interactions that assemble large oligomeric signaling complexes such as the inflammasomes during innate immune responses. Structural studies of the mammalian CARDs demonstrate that their six-helix bundle folds belong to the dea...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
International Union of Crystallography
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729158/ https://ncbi.nlm.nih.gov/pubmed/23908027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113015558 |
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