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Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1
The NLRP1 inflammasome responds to microbial challenges such as Bacillus anthracis infection and is implicated in autoimmune disease such as vitiligo. Human NLRP1 contains both an N-terminal pyrin domain (PYD) and a C-terminal caspase recruitment domain (CARD), with the latter being essential for it...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3860829/ https://ncbi.nlm.nih.gov/pubmed/23508996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24287 |
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