Crystal structure of zinc-finger domain of Nanos and its functional implications

Nanos is an RNA-binding protein that is involved in the development and maintenance of germ cells. In combination with Pumilio, Nanos binds to the 3′ untranslated region of a messenger RNA and represses its translation. Nanos has two conserved Cys-Cys-His-Cys zinc-finger motifs that are indispensabl...

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Détails bibliographiques
Auteurs principaux: Hashimoto, Hiroshi, Hara, Kodai, Hishiki, Asami, Kawaguchi, Shigeta, Shichijo, Naoki, Nakamura, Keishi, Unzai, Satoru, Tamaru, Yutaka, Shimizu, Toshiyuki, Sato, Mamoru
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2010
Sujets:
Scientific Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966957/
https://ncbi.nlm.nih.gov/pubmed/20948543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.155
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